Each pilosebaceous unit is formed by a hair follicle and a contiguous sebaceous gland which produces sebum. Healthy follicles open onto the outside, and the sebum produced moves to the surface of the skin, acting as a lubricant and contributing to the skin’s protective barrier function.
In acne, the opening of the pilosebaceous follicle becomes blocked with the build-up of dead cells, so sebum accumulates inside, forming comedones, or primary acne lesions.
The environment created inside the blocked follicle fosters the growth of Propionibacterium acnes (P. acnes), the bacteria that lives on the healthy skin but due to specific causes it can quickly proliferate giving rise to the onset of the inflammation, redness and lesions characteristic of acne.
Main factors causing acne-prone skin conditions:
Although acne usually begins in adolescence due to hormonal changes, and generally disappears around the age of 25, it continues to impact a considerable number of patients even after that age, and in particular women. This is due to genetic factors, hormone fluctuations, stress, and the use of certain cosmetics and medications.
Characterised by a build-up of cells and sebum inside the blocked follicles, but with no visible inflammation. These lesions are known as closed comedones and open comedones, or blackheads.
In addition to the build-up of cells and sebum inside the follicles, these lesions present bacterial infection (P. acnes) and inflammation. The lesions can be papules or pustules, depending on the degree of inflammation and, in more serious cases, nodules or cysts.
Acne can present different types of lesions, degrees of severity, and locations on the body, and can appear at different ages, all of which require specific intervention.
That’s why each patient must use the most suitable product. Biretix offers an extensive range for the comprehensive care of acne-prone skin, with specifically-formulated products depending on the type and location of the acne.